Category Chemistry

Terra Sigillata finds the right chemistry at CENtral Science

Update your bookmarks and RSS feeds Come to our new home at CENtral Science: Well, as I’ve been alluding to, I’ve decided to leave this state of indie blog purgatory and join CENtral Science, the blog platform of the American Chemical Society’s Chemical and Engineering News. C&EN is a weekly publication of the American […]

How to promote a science blogging network at a national scientific meeting

Bora Zivkovic, DrugMonkey, and I have been really impressed by this idea by the online folks over at the American Chemical Society’s Chemical & Engineering News. This week, their blog network, CENtral Science, has been promoting their presence at the upcoming national ACS meeting in Boston. Folks may not know this but ACS is the […]


Warning: rare self-indulgent post. Blogging has been and will be light over the next few days while we are packing up things around here to move to our next, more permanent home. In the meantime, you may have noticed here and on Twitter that part of my big news is that I will begin writing […]

Lunch-and-Learn with us next week in Boston at the American Chemical Society meeting

I’m really excited to be going up to Boston for a few days next week to attend the fall meeting of the American Chemical Society. Besides presenting some of our collaborative work, the highlight of my time there will be with Carmen Drahl of C&EN and The Haystack blog hosting a panel on chemistry and […]

K2 Spice associated with death of young Indiana mother of two

Welcome to readers arriving via Adam Brown’s referral from I’ve since moved my blog where I have written extensively on the fake weed phenomenon over the last year-and-a-half. Click here to read my compilation of synthetic marijuana posts at the new home of this blog.     From the overnight e-mail referrals of PharmGirl, […]

Sustained interest in K2 Spice, JWH-018, and related currently-legal cannabimimetic products

USA Today’s Donna Leinwand spoke yesterday of proposed K2 Spice bans across the US. But a careful analysis of our traffic raises questions as to whether the US military is about to make a move in this regard.

Sir James Black (1924-2010) – Physician, Pharmacologist, Gentleman

It is rare for a scientist to discover one drug that makes it to market. Sir James not only led the discovery of two major drugs, propranolol and cimetidine. As if that were not enough, each drug was a “first-in-class” agent, the first approved drug that acts via a novel mechanism of action.

Icariin from horny goat weed is structurally unrelated to sildenafil (Viagra®)

A follow-on discussion of Pfizer’s rejected patent claim and some molecular modeling thanks to valued readers, daedalus4u and Prof Ian Musgrave, respectively. You know, science blogging is cool.

Interview with Dr Ada Yonath, a 2009 Nobel Laureate in Chemistry

“No one wanted to believe it because they didn’t do it first”

Venkatraman Ramakrishnan, Thomas Steitz, and Ada Yonath win 2009 Nobel Prize in Chemistry

Yes, friends: this year’s Nobel Prize in Chemistry would not have been possible without the awesome power of natural products and the contributions of my natural products chemistry colleagues who provided Ramikrishnan, Steitz, and Yonath with the chemical tools for their work. “The ribosome is the target for about 50% of all antibacterial drugs to date, and the advent of high resolution structures of both ribosomal subunits has opened a large number of possibilities for [structure-based drug design] of new and effective drugs in the race against resistance development among bacterial pathogens.”


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